Demerol Injection is indicated for preoperative medication, support of anesthesia, and obstetrical analgesia. Tolterodine may cause a condition that affects the heart rhythm QT prolongation. Store at room temperature away from moisture and heat. iressa mail order pharmacy australia
Prolonged use of Demerol Injection during pregnancy can result in withdrawal in the neonate. Neonatal opioid withdrawal syndrome, unlike opioid withdrawal syndrome in adults, may be life-threatening if not recognized and treated, and requires management according to protocols developed by neonatology experts. Observe newborns for signs of neonatal opioid withdrawal syndrome and manage accordingly. Meperidine produces peripheral vasodilation which may result in orthostatic hypotension or syncope. Assess each patient's risk for opioid addiction, abuse, or misuse prior to prescribing Demerol Injection, and monitor all patients receiving Demerol Injection for the development of these behaviors and conditions.
In clinical studies reported in the literature, changes in several pharmacokinetic parameters with increasing age have been observed. The initial volume of distribution and steady-state volume of distribution may be higher in elderly patients than in younger patients. The free fraction of meperidine in plasma may be higher in patients over 45 years of age than in younger patients. Carpuject are packaged in a Slim-Pak tamper detection package. Note that a needle is not included. Opioids may also obscure the clinical course in a patient with a head injury. Avoid the use of Demerol Injection in patients with impaired consciousness or coma.
Take Detrol LA extended-release capsules by mouth with or without food. Candesartan belongs to a class of drugs called angiotensin receptor blockers ARBs. It works by relaxing vessels so can flow more easily. Some medical conditions may interact with Detrol LA extended-release capsules. Physical dependence may not occur to a clinically significant degree until after several days to weeks of continued opioid usage. An extra patient leaflet is available with Detrol LA extended-release capsules. Talk to your pharmacist if you have questions about this information.
Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Detrol LA extended-release capsules works best if it is taken at the same time each day. Kathleen Zelman, MPH, RD, Director of Nutrition, WebMD. Talk to your doctor or about lifestyle changes that might benefit you. All of these results will help the doctor figure out how best to treat you. Although the risk of addiction in any individual is unknown, it can occur in patients appropriately prescribed Demerol Injection. Addiction can occur at recommended dosages and if the drug is misused or abused. Demerol Injection exposes patients and other users to the risks of opioid addiction, abuse, and misuse, which can lead to overdose and death. This medication contains tolterodine. Do not take Detrol or Detrol LA if you are allergic to tolterodine or any ingredients contained in this drug. DEMEROL is not a trademark of Hospira. What should I avoid while taking tolterodine Detrol LA? Parenteral drug products should be inspected visually for particulate and discoloration prior to administration whenever solution and container permit. Detrol LA extended-release capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people. Your doctor will pass the scope through your bladder and ureter into your kidney. She uses a small basket to remove small stones. If the stones are larger, the doctor will pass a laser through the scope to break them up. Typically, you are able to go home on the same day. Consult your doctor before -feeding. Meperidine produces respiratory depression by direct action on brain stem respiratory centers. The respiratory depression involves a reduction in the responsiveness of the brain stem respiratory centers to both increases in carbon dioxide tension and electrical stimulation.
Do not use Demerol Injection in patients taking MAOIs or within 14 days of stopping such treatment. What is the most important information I should know about tolterodine Detrol LA? These help to strengthen the pelvic floor after childbirth. They also help prevent stress incontinence. Best of all, you can do Kegels anytime, anywhere. Inadvertent injection about a nerve trunk may result in sensory-motor paralysis which is usually, though not always, transitory. To prevent needle-stick injuries, needles should not be recapped, purposely bent, or broken by hand. Demerol Injection may impair the mental or physical abilities needed to perform potentially hazardous activities such as driving a car or operating machinery. Warn patients not to drive or operate dangerous machinery unless they are tolerant to the effects of Demerol Injection and know how they will react to the medication. cymbalta
Limit dosage and duration to the minimum required. Surgery: Another way doctors can get rid of a kidney stone is to cut a small hole in your back and through your kidney in order to remove the stone. If this procedure is done, you could have to stay in the hospital for several days. If there's a blockage, you may need surgery. If necessary, meperidine may be given intravenously, but the injection should be given very slowly, preferably in the form of a diluted solution. Rapid intravenous injection of narcotic analgesics, including meperidine, increases the incidence of adverse reactions; severe respiratory depression, apnea, hypotension, peripheral circulatory collapse, and cardiac arrest have occurred. Meperidine should not be administered intravenously unless a narcotic antagonist and the facilities for assisted or controlled respiration are immediately available. When meperidine is given parenterally, especially intravenously, the patient should be lying down. Demerol Injection is achieved. Similarly, discontinuation of a CYP3A4 inducer, such as rifampin, carbamazepine, and phenytoin, in DEMEROL-Injection treated patients may increase meperidine plasma concentrations and prolong opioid adverse reactions. Tolterodine is used to treat overactive bladder with symptoms of urinary frequency, urgency, and incontinence. In severe overdose, particularly by the intravenous route, apnea, circulatory collapse, cardiac arrest, and death may occur. About FAERS: The FDA Adverse Event Reporting System FAERS is used by FDA for activities such as looking for new safety concerns that might be related to a marketed product, evaluating a manufacturer's compliance to reporting regulations and responding to outside requests for information. Reporting of adverse events is a voluntary process, and not every report is sent to FDA and entered into FAERS. If you are in really bad pain, you probably want to see a doctor. The safety and efficacy of Demerol Injection in patients less than 18 years of age have not been established. The major hazards of meperidine, as with other opioid analgesics, are respiratory depression and, to a lesser degree, circulatory depression; respiratory arrest, shock, and cardiac arrest have occurred. Store Detrol LA extended-release capsules at room temperature, between 68 and 77 degrees F 20 and 25 degrees C. Brief storage at temperatures between 59 and 86 degrees F 15 and 30 degrees C is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Detrol LA extended-release capsules out of the reach of children and away from pets. brand sotalol brands sotalol
Other. Pain at injection site; local tissue irritation and induration following subcutaneous injection, particularly when repeated; antidiuretic effect. Both tolerance and physical dependence can develop during chronic opioid therapy. Tolerance is the need for increasing doses of opioids to maintain a defined effect such as analgesia in the absence of disease progression or other external factors. Tolerance may occur to both the desired and undesired effects of drugs, and may develop at different rates for different effects. Adrenal insufficiency: Cases of adrenal insufficiency have been reported with opioid use, more often following greater than one month of use. PREGNANCY and BREAST-FEEDING: If you think you may be pregnant, contact your doctor. You will need to discuss the benefits and risks of using Detrol LA extended-release capsules while you are pregnant. It is not known if this medicine is found in breast milk. Do not breast-feed while taking Detrol LA extended-release capsules. The concomitant use of Demerol Injection with all cytochrome P450 3A4 inhibitors may result in an increase in meperidine plasma concentrations, which could increase or prolong adverse reactions and may cause potentially fatal respiratory depression. In addition, discontinuation of a concomitantly used cytochrome P450 3A4 inducer may result in an increase in meperidine plasma concentration. If you miss a dose, use it as soon as you remember. If it is near the time of the next dose, skip the missed dose and resume your usual dosing schedule. Pfizer also has programs that provide eligible patients with insurance support, copay assistance, and medicines for free. Other medications can affect the removal of from your body, which may affect how methylprednisolone works. Do not start, stop, or change the dosage of any medicines without your doctor's approval. The meperidine in Demerol Injection may cause spasm of the sphincter of Oddi. Opioids may cause increases in serum amylase. Monitor patients with biliary tract disease, including acute pancreatitis, for worsening symptoms. Avoid becoming overheated in hot weather, saunas, and during or other strenuous activity. Older adults may be more sensitive to the side effects of this drug, especially QT prolongation see above drowsiness, confusion, constipation, or trouble urinating. Drowsiness and confusion can increase the risk of falling. If concomitant use cimetidine and Demerol Injection is necessary, monitor patients for respiratory depression and sedation at frequent intervals. Think about stirring up your favorite drink from a powder mix. buy pure betapace
Consult your pharmacist for further advice. Do 3 or 4 sets daily. What happens if I miss a dose Detrol? Severe allergic reactions rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, throat, or tongue; unusual hoarseness; chest pain; confusion, disorientation, or memory problems; difficult or painful urination; fast or irregular heartbeat; fainting; hallucinations; severe dizziness; swelling of the hands, ankles, or feet. Then, if needed, she will order tests to get pictures of your kidneys and urinary tract. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or discontinuing any drug or commencing any course of treatment. Tell your doctor if your condition persists or worsens. If you miss a dose, take it as soon as you remember. If it is near the time of the next dose, skip themissed dose and resume your usual dosing schedule. It may rarely harm an unborn baby. Discuss the risks and benefits with your doctor. Infants born to mothers who have been using this medication for a long time may have problems. The use of Demerol Injection in patients with acute or severe bronchial asthma in an unmonitored setting or in the absence of resuscitative equipment is contraindicated. stock price for cefadroxil cefadroxil
Pfizer also has programs that provide eligible patients with insurance, support assistance, and medicines at a savings. Contact Pfizer RxPathways for details 844-989-7284. For certain products of this drug, an empty tablet shell may appear in your stool. This is harmless. Cut back on sodium and salty foods: Lots of sodium can raise calcium levels in your urine. And that can cause stones to form. If concomitant use of acyclovir and Demerol Injection is necessary, monitor patients for respiratory depression and sedation at frequent intervals. If you have any questions about Detrol LA extended-release capsules, please talk with your doctor, pharmacist, or other health care provider. How should I take tolterodine Detrol LA? Taking flecainide with other agents that can affect your heart rhythm may increase your risk of an irregular heartbeat, which may be life-threatening. The opinions expressed in WebMD User-generated content areas like communities, reviews, ratings, or blogs are solely those of the User, who may or may not have medical or scientific training. These opinions do not represent the opinions of WebMD. User-generated content areas are not reviewed by a WebMD physician or any member of the WebMD editorial staff for accuracy, balance, objectivity, or any other reason except for compliance with our Terms and Conditions. Methylprednisolone may make you dizzy. not drive, use machinery, or do any activity that requires alertness until you are sure you can perform such activities safely. Drug addiction is a cluster of behavioral, cognitive, and physiological phenomena that develop after repeated substance use and includes a strong desire to take the drug, difficulties in controlling its use, persisting in its use despite harmful consequences, a higher priority given to drug use than to other activities and obligations, increased tolerance, and sometimes a physical withdrawal. Formal reproductive and developmental toxicology studies for meperidine have not been completed. You should not take this medication if you are allergic to tolterodine or fesoterodine Toviaz if you have untreated or uncontrolled narrow-angle glaucoma, or if you have a blockage of the urinary tract, stomach, or intestines.
DEMEROL meperidine hydrochloride, USP Injection is an opioid agonist, available for intramuscular, intravenous, or subcutaneous administration. Overestimating the Demerol Injection dosage when converting patients from another opioid product can result in a fatal overdose with the first dose. Meperidine appears in the milk of nursing mothers receiving the drug. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for Demerol Injection and any potential adverse effects on the breastfed infant from Demerol Injection or from the underlying maternal condition. In patients with pheochromocytoma, meperidine has been reported to provoke hypertension. The dosage is based on your medical condition and response to treatment. Drink plenty of water: You should drink at least 64 ounces of water each day. Some of that liquid can be orange juice, lemonade, or limeade. Demerol Injection contains meperidine, a substance with a high potential for abuse similar to other opioids including fentanyl, hydrocodone, hydromorphone, methadone, morphine, oxycodone, oxymorphone, and tapentadol. The dose of Demerol Injection should be proportionately reduced usually by 25 to 50 percent when administered concomitantly with phenothiazines and many other tranquilizers since they potentiate the action of Demerol Injection. How should I take tolterodine Detrol? Opioids cross the placenta and may produce respiratory depression and psycho-physiologic effects in neonates. An opioid antagonist, such as naloxone, must be available for reversal of opioid-induced respiratory depression in the neonate. Demerol Injection is not recommended for use in pregnant women during or immediately prior to labor, when other analgesic techniques are more appropriate. Opioid analgesics, including Demerol Injection, can prolong labor through actions which temporarily reduce the strength, duration, and frequency of uterine contractions. However, this effect is not consistent and may be offset by an increased rate of cervical dilation, which tends to shorten labor. Monitor neonates exposed to opioid analgesics during labor for signs of excess sedation and respiratory depression. Adults: The usual dosage is 50 mg to 100 mg intramuscularly or subcutaneously, 30 to 90 minutes before the beginning of anesthesia. Elderly patients should usually be given meperidine at the lower end of the dose range and observed closely. Inform patients that opioids could cause a rare but potentially life-threatening condition resulting from concomitant administration of serotonergic drugs. Warn patients of the symptoms of serotonin syndrome and to seek medical attention right away if symptoms develop. When a patient who has been taking Demerol Injection regularly and may be physically dependent no longer requires therapy with Demerol Injection, taper the dose gradually, by 25% to 50% every 2 to 4 days, while monitoring carefully for signs and symptoms of withdrawal. If the patient develops these signs or symptoms, raise the dose to the previous level and taper more slowly, either by increasing the interval between decreases, decreasing the amount of change in dose, or both. Tolterodine may also be used for purposes not listed in this medication guide. frol.info cefaclor
This medicine may cause bleeding. Daily use of alcohol while using this medicine may increase your risk for stomach bleeding. During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. The half-life of meperidine is 2 to 5 hours, and the half-life of normeperidine is 15 to 30 hours. Hold the squeeze for 10 seconds, then rest for 10 seconds. While many dieters swear by high-, eating large amounts of can also cause a stone to form. Your pharmacist can provide more information about tolterodine. Proper assessment of the patient, proper prescribing practices, periodic re-evaluation of therapy, and proper dispensing and storage are appropriate measures that help to limit abuse of opioid drugs. All patients treated with opioids require careful monitoring for signs of abuse and addiction, since use of opioid analgesic products carries the risk of addiction even under appropriate medical use. This may occur within the recommended dosage range. Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your or local waste disposal company. UpToDate: "Nutrition and Dietary Interventions in Adults with Inflammatory Bowel Disease. cheapest glimepiride uk
Side Effects List Detrol LA side effects by likelihood and severity. Demerol Injection contains meperidine, a Schedule II controlled substance. Once you have passed the stone, the doctor will have it analyzed to figure out what it was made of. You also might need to collect your pee for 24 hours to have it tested. Many drugs besides tolterodine may affect the heart rhythm QT prolongation including amiodarone, dofetilide, pimozide, procainamide, quinidine, sotalol, macrolide antibiotics such as erythromycin among others. The most frequently observed adverse reactions include lightheadedness, dizziness, sedation, nausea, vomiting, and sweating. These effects seem to be more prominent in ambulatory patients and in those who are not experiencing severe pain. In such individuals, lower doses are advisable. Some adverse reactions in ambulatory patients may be alleviated if the patient lies down. Your doctor may want you to save the stone so it can be tested. If she can figure out what kind of stone it is, that may help prevent you from having another one. buy tricor reacoes
Monitor for signs of opioid withdrawal. Contact local state professional licensing board or state controlled substances authority for information on how to prevent and detect abuse or diversion of this product. Check the Rx Outreach website for the exact price and most current medication list. Accumulation of normeperidine as in chronic use or possibly following introduction of a concomitant CYP3A4 inducer presents as excitatory syndrome including hallucinations, tremors, muscle twitches, dilated pupils, hyperactive reflexes, and convulsions. Your doctor may occasionally change your dose to make sure you get the best results. The meperidine in Demerol Injection may increase the frequency of seizures in patients with seizure disorders, and may increase the risk of seizures occurring in other clinical settings associated with seizures. Monitor patients with a history of seizure disorders for worsened seizure control during Demerol Injection therapy. Oro Valley, AZ 85755. November 17, 2015. Remember that your doctor has prescribed this because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication not have serious side effects. Meperidine should therefore be used with caution in patients with renal impairment. Titrate the dosage of Demerol Injection slowly in patients with renal impairment and monitor closely for signs of central nervous system and respiratory depression. Phenytoin: The hepatic metabolism of meperidine may be enhanced by phenytoin. This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. You'll through this procedure. If any of these effects persist or worsen, tell your doctor or promptly. Prolonged use of opioid analgesics during pregnancy for medical or nonmedical purposes can result in physical dependence in the neonate and neonatal opioid withdrawal syndrome shortly after birth. Catheter. Some people use a catheter to make sure their bladder is emptied. It's a thin plastic tube that you insert in your urethra. A doctor or nurse can teach you how to insert it for yourself. Some MEDICINES MAY INTERACT with Detrol LA extended-release capsules. pletal
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Do not stop taking this medication without consulting your doctor. This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist. The following adverse reactions associated with the use of meperidine were identified in clinical studies or postmarketing reports. Because some of these reactions were reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. WebMD User Reviews should not be considered as medical advice and are not a substitute for professional medical advice, diagnosis, or treatment. Never delay or disregard seeking professional medical advice from your physician or other qualified healthcare provider because of something you have read on WebMD. You should always speak with your doctor before you start, stop, or change any prescribed part of your care plan or treatment. WebMD understands that reading individual, real-life experiences may be a helpful health information resource but they are never a substitute for professional medical advice from a qualified healthcare provider. cafergot
Oxybutynin belongs to a class of drugs known as antispasmodics. FDA pregnancy category C. It is not known whether tolterodine will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Blunt cannulas should not be recapped, purposely bent or broken by hand. cheap combigan wikipedia
Tolterodine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Follow patients for signs and symptoms of respiratory depression and sedation. Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Symptoms can vary and can range in severity.
Do not crush, chew, break, or open a controlled-release capsule. Swallow it whole. Breaking or opening the pill may cause too much of the drug to be released at one time. These are the most common ones. Respiratory depression is the chief risk for elderly patients treated with opioids, and has occurred after large initial doses were administered to patients who were not opioid-tolerant or when opioids were co-administered with other agents that depress respiration.